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Like all other health-supplements and medicines, Plavix too must be taken strictly as per the instructions of the medical practitioner General Information on Plavix. Mechanism of action Selectively and irreversibly inhibits ADP-induced platelet aggregation by inhibiting the binding of ADP to its receptors on platelets, thereby affecting ADP-dependent activation of the glycoprotein IIb / IIIa complex, the major site of platelet-fibrinogen binding Clopidogrel will help prevent serious problems with your heart and blood vessels only as long as you take the medication. Initiating Plavix without a loading dose will delay establishment of an antiplatelet effect by several days [see CLINICAL PHARMACOLOGY and …. 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Like all other health-supplements and medicines, Plavix too must be taken strictly as per the instructions of the medical practitioner General Information on Plavix. Mechanism of action Selectively and irreversibly inhibits ADP-induced platelet aggregation by inhibiting the binding of ADP to its receptors on platelets, thereby affecting ADP-dependent activation of the glycoprotein IIb / IIIa complex, the major site of platelet-fibrinogen binding Clopidogrel will help prevent serious problems with your heart and blood vessels only as long as you take the medication. Initiating Plavix without a loading dose will delay establishment of an antiplatelet effect by several days [see CLINICAL PHARMACOLOGY and …. 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